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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VDAC1
All Species:
43.64
Human Site:
S193
Identified Species:
73.85
UniProt:
P21796
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21796
NP_003365.1
283
30773
S193
D
G
T
E
F
G
G
S
I
Y
Q
K
V
N
K
Chimpanzee
Pan troglodytes
XP_001151901
283
30732
S193
D
G
T
E
F
G
G
S
I
Y
Q
K
V
N
K
Rhesus Macaque
Macaca mulatta
XP_001107652
283
30703
S193
D
G
T
E
F
G
G
S
I
Y
Q
K
V
N
K
Dog
Lupus familis
XP_536597
256
28121
T182
T
D
E
F
Q
L
H
T
N
V
N
D
G
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q60932
296
32333
S206
D
G
T
E
F
G
G
S
I
Y
Q
K
V
N
K
Rat
Rattus norvegicus
Q9Z2L0
283
30737
S193
D
G
T
E
F
G
G
S
I
Y
Q
K
V
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510394
343
37536
S206
D
G
T
E
F
G
G
S
I
Y
Q
K
V
N
K
Chicken
Gallus gallus
NP_001029041
283
30688
S193
D
G
T
E
F
G
G
S
I
Y
Q
K
V
N
E
Frog
Xenopus laevis
P81004
282
30052
S192
D
G
S
E
F
A
G
S
I
Y
Q
K
V
S
D
Zebra Danio
Brachydanio rerio
NP_001001404
283
30608
S193
D
G
T
E
F
G
G
S
I
Y
Q
K
V
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94920
282
30532
S192
D
G
Q
E
F
S
G
S
I
F
Q
R
T
S
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21752
283
29942
S193
N
S
T
D
F
G
A
S
L
Y
H
K
V
A
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P04840
283
30410
D191
N
E
Q
I
T
T
V
D
F
F
Q
N
V
N
A
Red Bread Mold
Neurospora crassa
P07144
283
29981
Y193
L
S
V
F
S
A
S
Y
Y
H
K
V
N
S
Q
Conservation
Percent
Protein Identity:
100
98.9
99.2
86.2
N.A.
94.2
98.5
N.A.
72.3
95.4
75.6
85.5
N.A.
58.2
N.A.
40.6
N.A.
Protein Similarity:
100
98.9
99.6
87.2
N.A.
95.2
99.6
N.A.
77.2
98.2
91.8
93.6
N.A.
75.9
N.A.
60.4
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
100
93.3
73.3
93.3
N.A.
53.3
N.A.
46.6
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
100
100
86.6
93.3
N.A.
73.3
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.4
31.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47
51.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
15
8
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
72
8
0
8
0
0
0
8
0
0
0
8
0
0
22
% D
% Glu:
0
8
8
72
0
0
0
0
0
0
0
0
0
0
15
% E
% Phe:
0
0
0
15
79
0
0
0
8
15
0
0
0
0
0
% F
% Gly:
0
72
0
0
0
65
72
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
8
8
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
72
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
72
0
0
43
% K
% Leu:
8
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
0
0
8
0
8
8
8
65
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
15
0
8
0
0
0
0
0
79
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
15
8
0
8
8
8
79
0
0
0
0
0
22
8
% S
% Thr:
8
0
65
0
8
8
0
8
0
0
0
0
8
8
0
% T
% Val:
0
0
8
0
0
0
8
0
0
8
0
8
79
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
8
72
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _